دورية أكاديمية
Dupilumab‐induced psoriasiform dermatitis in two pediatric cardiac transplant patients.
| العنوان: | Dupilumab‐induced psoriasiform dermatitis in two pediatric cardiac transplant patients. |
|---|---|
| المؤلفون: | Lockard, Trevor, Mullen, Sarah A., Lee, Erica B., Niebur, Hana, Harter, Nicole |
| المصدر: | Pediatric Dermatology; May2024, Vol. 41 Issue 3, p508-511, 4p |
| مصطلحات موضوعية: | HEART transplantation, DRUG side effects, SKIN inflammation, CARDIAC patients, DRUG eruptions |
| مستخلص: | Dupilumab is an interleukin‐4 receptor antagonist important in the treatment of refractory atopic dermatitis (AD), particularly among pediatric patients. Two boys with a history of AD and cardiac transplant who developed psoriasiform dermatitis in response to dupilumab therapy are reported. These patients paradoxically developed an immune‐mediated adverse drug reaction despite taking systemic immunosuppressive agents. While the literature suggests possible pathomechanisms for psoriasiform dermatitis despite immunosuppression, further research is necessary to better characterize this unique and unexpected phenomenon. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: | Complementary Index |
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