دورية أكاديمية
Role of β3 subunit of the GABA type A receptor in triple negative breast cancer proliferation, migration, and cell cycle progression.
العنوان: | Role of β3 subunit of the GABA type A receptor in triple negative breast cancer proliferation, migration, and cell cycle progression. |
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المؤلفون: | Bundy, J, Shaw, J, Hammel, M, Nguyen, J, Robbins, C, Mercier, I, Suryanarayanan, A |
المصدر: | Cell Cycle; Feb2024, Vol. 23 Issue 4, p448-465, 18p |
مصطلحات موضوعية: | TRIPLE-negative breast cancer, GABA receptors, CELL cycle, LIGAND-gated ion channels, CANCER cell growth, ION channels |
مستخلص: | Triple negative breast cancer (TNBC) is known for its heterogeneous nature and aggressive onset. The unresponsiveness to hormone therapies and immunotherapy and the toxicity of chemotherapeutics account for the limited treatment options for TNBC. Ion channels have emerged as possible therapeutic candidates for cancer therapy, but little is known about how ligand gated ion channels, specifically, GABA type A ligand-gated ion channel receptors (GABA |
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قاعدة البيانات: | Complementary Index |
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