التفاصيل البيبلوغرافية
| العنوان: |
Understanding the anatomy of dermoscopy of melanocytic skin tumours: Correlation in vivo with line‐field optical coherence tomography. |
| المؤلفون: |
Soglia, S., Pérez‐Anker, J., Albero, R., Alós, L., Berot, V., Castillo, P., Cinotti, E., Del Marmol, V., Fakih, A., García, A., Lenoir, C., Monnier, J., Perrot, J. L., Puig, S., Rubegni, P., Skowron, F., Suppa, M., Tognetti, L., Venturini, M., Malvehy, J. |
| المصدر: |
Journal of the European Academy of Dermatology & Venereology; Jun2024, Vol. 38 Issue 6, p1191-1201, 11p |
| مصطلحات موضوعية: |
OPTICAL coherence tomography, RETINAL imaging, DERMOSCOPY, CONFOCAL microscopy, ANATOMY, PANCREATIC cysts |
| مستخلص: |
Background: Early melanoma detection is the main factor affecting prognosis and survival. For that reason, non‐invasive technologies have been developed to provide a more accurate diagnosis. Recently, line‐field confocal optical coherence tomography (LC‐OCT) was developed to provide an in vivo, imaging device, with deep penetration and cellular resolution in three dimensions. Combining the advantages of conventional OCT and reflectance confocal microscopy, this tool seems to be particularly suitable for melanocytic lesions. Objectives: The objective of this study was to identify and describe the correlation between specific dermoscopic criteria and LC‐OCT features in three dimensions associated with melanocytic lesions. Methods: Dermoscopic and LC‐OCT images of 126 melanocytic lesions were acquired in three different centres. The following dermoscopic criteria have been considered: reticular pattern, dots and globules, structureless areas, blue‐whitish veil, regression structures, negative network, homogeneous pattern, streaks and blotches. Results: 69 (55%) benign and 57 (45%) malignant lesions were analysed. A regular reticular pattern was found associated in the 75% of the cases with the presence of elongated rete ridges with pigmented cells along the basal layer, while atypical reticular pattern showed an irregular organization of rete ridges with melanocytic hyperplasia, broadened and fused ridges and elongated nests. Both typical and atypical dots and globules were found associated with melanocytic nests in the dermis or at the dermoepidermal junction (DEJ), as well as with keratin cysts/pseudocysts. Grey globules corresponded to the presence of melanin‐containing dermal inflammatory cells (melanophages) within the papillae. Structureless brown/black areas correlated with alterations of the DEJ. We observed the same DEJ alterations, but with the presence of dermal melanophages, in 36% of the cases of blue/white/grey structureless areas. A description of each LC‐OCT/dermoscopy correlation was made. Conclusions: LC‐OCT permitted for the first time to perform an in vivo, 3D correlation between dermoscopic criteria and pathological‐like features of melanocytic lesions. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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