التفاصيل البيبلوغرافية
| العنوان: |
L-LOP/LOPP for the treatment of canine gastrointestinal/ hepatosplenic lymphoma. |
| المؤلفون: |
Yu Ying Lai, Horta, Rodrigo dos Santos, Almendros, Angel, Ha, Patrick W. Y., Giuliano, Antonio |
| المصدر: |
Frontiers in Veterinary Science; 2024, p01-08, 8p |
| مصطلحات موضوعية: |
LYMPHOMAS, PROGRESSION-free survival, SURVIVAL rate, MAST cell tumors, MEDICAL protocols, PROGNOSIS |
| مستخلص: |
Canine gastrointestinal (GI) and hepatosplenic (HS) high-grade (large cell) lymphomas are uncommon forms of canine lymphomas, with a very poor response to chemotherapy and a very poor prognosis. Currently, there are no established effective chemotherapy protocols for canine GI/HS lymphomas. This case series aimed to retrospectively evaluate the efficacy of lomustine-based protocols L-LOP (L-asparaginase, lomustine, vincristine, and prednisolone) and L-LOPP (with the addition of procarbazine) for treatment of canine GI/ HS lymphomas. Medical records of dogs with cytologically or histologically diagnosed lymphoma at CityU Veterinary Medical Centre from 2019 to 2022 were retrospectively reviewed. The L-LOP/LOPP treatment protocol was well tolerated with rare severe adverse events. Median progression-free survival for GI and HS lymphoma was 56 days (range, 10-274 days) and 57 days (range 8-135 days) respectively; while median survival time for GI and HS lymphoma was 93 days (range 10-325 days) and 210 days (range 8-240 days) respectively. [ABSTRACT FROM AUTHOR] |
|
Copyright of Frontiers in Veterinary Science is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder