دورية أكاديمية
Hericium VN, an undescribed compound isolated from Hericium erinaceus and its cytotoxic activity on human brain astrocytoma.
| العنوان: | Hericium VN, an undescribed compound isolated from Hericium erinaceus and its cytotoxic activity on human brain astrocytoma. |
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| المؤلفون: | Mai Huong, Le, Huu Nghi, Do, Dinh Luyen, Nguyen, Thu Quynh, Dang, Huong, Phan Thi Thanh, Tai, Bui Huu, Kiem, Phan Van |
| المصدر: | Journal of Asian Natural Products Research; Jul2024, Vol. 26 Issue 7, p850-857, 8p |
| مصطلحات موضوعية: | EDIBLE mushrooms, GLIOMAS, NUCLEAR magnetic resonance spectroscopy, RESEARCH funding, APOPTOSIS, FUNGI, PLANT extracts, CELL lines, INFRARED spectroscopy, MOLECULAR structure, BIOLOGICAL assay, BRAIN tumors |
| مستخلص: | Hericium erinaceus is a species of mushroom with high nutritional value that is used mainly as food in tropical countries. Phytochemical study of H. erinaceus led to the isolation of an undescribed compound, named as hericium VN (1), together with nine known compounds, 1-(2-formyl-1-pyrrolyl)butanoic acid (2), herierin III (3), 5′-(methylthio)adenosine (4), adenosine (5), nicotinic acid (6), (22E,24R)-5α,8α-epidioxyergosta-6,9(11),22-trien-3β-ol (7), 5α,8α-peroxycerevisterol (8), (22E,24R)-5α,8α-epidioxy-egosta-6,22-diene 3-O-β-D-glucopyranoside (9), and cerevisterol (10) based on extensive analyses of HR-ESI-MS, 1D and 2D NMR spectra. The absolute configuration of compound 1 was determined by experimental combined with calculated electronic circular dichroism spectra. Compound 7 exhibited cytotoxic effects against brain tumor cell line CCF-STTG1 with the IC |
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| قاعدة البيانات: | Complementary Index |
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