التفاصيل البيبلوغرافية
| العنوان: |
Sugar-sweetened beverage but not diluted cloudy apple juice consumption induces post-prandial endotoxemia in healthy adults. |
| المؤلفون: |
Staltner, Raphaela, Valder, Sarah, Wodak, Maximilian F., Köpsel, Magdalena, Herdegen, Volker, Esatbeyoglu, Tuba, Kostov, Tihomir, Diel, Patrick, Bergheim, Ina |
| المصدر: |
NPJ Science of Food; 6/21/2024, Vol. 8 Issue 1, p1-8, 8p |
| مصطلحات موضوعية: |
INTESTINAL barrier function, ENDOTOXEMIA, SOFT drinks, BACTERIAL toxins, APPLE juice, ADULTS, FRUIT juices |
| مستخلص: |
Sugar beverages are discussed as critical in the development of metabolic endotoxemia. Here, employing a cross-over design study we assessed the effect of diluted cloudy apple juice (AJ), an iso-caloric and -sweetened placebo (P), or water (W) on post-prandial endotoxemia in healthy, normal weight adults. After obtaining fasting blood, 19 healthy men and women consumed 500 mL AJ, P, or W in a randomized order and blood was taken 120 and 180 min later. Caco-2 cells were incubated with the beverages. Markers of intestinal barrier function were assessed. The intake of P but not of AJ or W was associated with a significant increase in TLR2 ligands and bacterial endotoxin in serum after 120 min and 180 min, respectively. P but not AJ significantly increased bacterial toxin permeation in Caco-2 cells. Our results suggest that the effects of sugar-sweetened beverages on markers of intestinal barrier function markedly differ from those of fruit juices. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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