دورية أكاديمية

Crusted Scabies in a Pediatric Liver Transplant Recipient on Immunosuppression.

التفاصيل البيبلوغرافية
العنوان: Crusted Scabies in a Pediatric Liver Transplant Recipient on Immunosuppression.
المؤلفون: Goh, Laura Shih Hui, Karthik, Sivaramakrishnan Venkatesh, Nor, Nur Hafizah Mohamed, Loh, Dale Lincoln Ser Kheng, Mali, Vidyadhar Padmakar
المصدر: American Journal of Case Reports; 7/7/2024, Vol. 25, p1-5, 5p
مصطلحات موضوعية: SCABIES, LIVER transplantation, SARCOPTES scabiei, SYMPTOMS, IMMUNOCOMPROMISED patients, SKIN infections
مستخلص: Objective: Unusual clinical course Background: Crusted scabies is a severe skin infection resulting from hyper-infestation with the obligate parasite Sarcoptes scabiei var. hominis. In contrast to classic scabies, crusted scabies may involve as many as hundreds to millions of mites. Importantly, this condition is associated with a mortality rate of 60% in 5 years, and is more likely to develop in immunosuppressed hosts, presumably due to an impaired T-cell response against the mite. Case Report: We present a case of crusted scabies in a 13-year-old girl during her early post-liver transplant period receiving immunosuppression successfully treated with topical 5% permethrin. She had pruritic erythematous papules, confirmed as scabies through skin scraping. The challenge of misdiagnosis during the initial presentation is noteworthy, given atypical manifestations and more common differentials. To our knowledge, only 2 cases of crusted scabies in pediatric solid-organ transplant recipients have been reported. Despite the absence of guidelines for pediatric solid-organ transplant recipients, urgent treatment is required due to the high mortality rates associated with crusted scabies. In our case, early treatment proved successful without any secondary bacterial infections or clinical evidence of relapse during a 6-month follow-up. Conclusions: We report a case of scabies in a pediatric liver transplant recipient that was successfully treated. It is crucial to consider the diagnosis of scabies given the associated morbidity and the risk of secondary bacterial infections among other more common differentials. Notably, the response to standard anti-scabies treatment may lead to resolution without relapse in pediatric solid-organ transplant recipients. [ABSTRACT FROM AUTHOR]
Copyright of American Journal of Case Reports is the property of International Scientific Literature, Inc and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index