التفاصيل البيبلوغرافية
| العنوان: |
Complete Thoracic Ectopia Cordis in Two Lambs. |
| المؤلفون: |
Cerqueira, Liz de Albuquerque, Mâcedo, Isabel Luana de, Sousa, Davi Emanuel Ribeiro de, Amorim, Haiane Arruda Luz, Borges, José Renato Junqueira, Ximenes, Fábio Henrique Bezerra, Câmara, Antonio Carlos Lopes, Castro, Márcio Botelho de |
| المصدر: |
Animals (2076-2615); Aug2024, Vol. 14 Issue 15, p2213, 8p |
| مصطلحات موضوعية: |
CONGENITAL heart disease, HUMAN abnormalities, TERATOGENESIS, SHEEP, NEWBORN infants |
| مستخلص: |
Simple Summary: This report characterized complete thoracic ectopia cordis (EC) affecting two newborn lambs from different locations in Brazil, contributing to the knowledge about this rare condition in sheep. Two male newborn lambs presented exteriorized hearts without pericardial coverage, delineated in the thoracic cleft by a fibrous ring of the pericardium and adjacent skin. Clinical findings in the lambs, aside from the EC, were unremarkable. EC is an extremely rare congenital malformation in sheep, with limited cases documented globally. The pathogenesis and etiology remain uncertain, involving potential genetic and environmental factors. Cardiac congenital defects related to inheritance and teratogenesis have been reported in veterinary species and humans worldwide. Among these, ectopia cordis (EC), characterized by an externalized heart through a cleft, is extremely rare in sheep. This report presents the diagnostic features of two cases of complete thoracic EC in newborn lambs. Clinical findings in the lambs, aside from the EC, were unremarkable. Both animals exhibited exteriorized hearts without pericardial coverage, delineated in the thoracic cleft by a fibrous ring of the pericardium and adjacent skin. Histologically, the epicardium was thickened by fibrous tissue in both lambs, with one animal also showing marked edema, hemorrhage, and neutrophilic inflammatory infiltration. The prognosis of EC in the lambs of this study was poor, with fatal outcomes despite attempts at surgical correction. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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