دورية أكاديمية
Delphinidin and cyanidin inhibit PDGFAB-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK.
العنوان: | Delphinidin and cyanidin inhibit PDGF |
---|---|
المؤلفون: | Oak, M.-H., Bedoui, J. E., Madeira, S. V. F., Chalupsky, K., Schini-Kerth, V. B. |
المصدر: | British Journal of Pharmacology; Oct2006, Vol. 149 Issue 3, p283-290, 8p |
مصطلحات موضوعية: | POLYPHENOLS, VASCULAR endothelial growth factors, VASCULAR smooth muscle, BLOOD vessels, REACTIVE oxygen species, FLAVONOIDS |
مستخلص: | Background and purpose: Red wine polyphenols (RWPs) inhibit the expression of vascular endothelial growth factor (VEGF), a major pro-angiogenic and pro-atherosclerotic factor, in vascular smooth muscle cells (VSMCs). The aim of this study was to identify which red wine polyphenols were inhibitory and to determine the mechanism underlying the inhibitory effects. Experimental approach: Release of VEGF stimulated by platelet derived growth factor |
Copyright of British Journal of Pharmacology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
قاعدة البيانات: | Complementary Index |
كن أول من يترك تعليقا!