دورية أكاديمية
The higher level of organization of the oxidative phosphorylation system: mitochondrial supercomplexes.
| العنوان: | The higher level of organization of the oxidative phosphorylation system: mitochondrial supercomplexes. |
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| المؤلفون: | Natalya Dudkina, Stephanie Sunderhaus, Egbert Boekema, Hans-Peter Braun |
| المصدر: | Journal of Bioenergetics & Biomembranes; Oct2008, Vol. 40 Issue 5, p419-424, 6p |
| مصطلحات موضوعية: | PHOSPHORYLATION, CHEMICAL reactions, MITOCHONDRIAL membranes, POLYACRYLAMIDE |
| مستخلص: | Abstract  The organization of the oxidative phosphorylation (OXPHOS) system within the inner mitochondrial membrane appears to be far more complicated than previously thought. In particular, the individual protein complexes of the OXPHOS system (complexes I to V) were found to specifically interact forming defined supramolecular structures. Blue-native polyacrylamide gel electrophoresis and single particle electron microscopy proved to be especially valuable in studying the so-called ârespiratory supercomplexesâ. Based on these procedures, increasing evidence was presented supporting a âsolid stateâ organization of the OXPHOS system. Here, we summarize results on the formation, organisation and function of the various types of mitochondrial OXPHOS supercomplexes. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: | Complementary Index |
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