التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of methods of assisted ventilation in hyaline membrane disease. |
| المؤلفون: |
MANGINELLO, FRANK P., GRASSI, ARMANDO E., SCHECHNER, SYLVIA, KRAUSS, ALFRED N., AULD, PETER A. M., Manginello, F P, Grassi, A E, Schechner, S, Krauss, A N, Auld, P A |
| المصدر: |
Archives of Disease in Childhood; Nov1978, Vol. 53 Issue 11, p878-881, 4p, 2 Charts, 2 Graphs |
| مستخلص: |
Two methods of providing assisted ventilation were compared in infants severely ill with hyaline membrane disease (HMD). 10 infants were assigned to each group. One group received ventilation with a volume-cycled respirator, and the other was ventilated using a pressure-limited ventilator and reversed I:E ratio. Both groups were well matched for severity of illness in terms of pH and blood gases. pH and PO2 were quickly corrected by both ventilators. However, the pressure-cycled ventilator group had higher survival and lower complication rates. PAO2 after one hour was substantially improved at the same FIO2 in the pressure-limited group and after 8 hours the FIO2 required to maintain a PaO2 of 50--70 mmHg (6.6--9.3 kPa) was significantly decreased compared with the volume-cycled group. No effects on blood pressure were detected in either group. The study shows that the pressure-limited method is significantly better. [ABSTRACT FROM AUTHOR] |
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