التفاصيل البيبلوغرافية
| العنوان: |
Fatigue of the cochlear nerve by intense pure tones: Invariance of the half-octave shift. |
| المؤلفون: |
Meikle, M. B., Lee, C. A. |
| المصدر: |
Journal of the Acoustical Society of America; 1978, Vol. 64 Issue S1, pS135-S136, 2p |
| مستخلص: |
In earlier work it was shown that pure tone overloads at 3, 6, and 12 kHz produced maximal neural depression at 1/2 octave above the exposure frequency [C. Mitchell et al., J. Acoust. Soc. Am. 53, 326 (1973)]. The present experiments were designed to determine whether or not the exact frequency at which maximum depression occurs is dependent upon the intensity of the exposure. Summated action potentials (APs) of the cochlear nerve were measured in guinea pigs before and after exposure to intense pure tones. These frequency-specific APs were elicited by carefully-shaped tone bursts (10 msec duration, 1 msec rise-decay) at 32 frequencies at 1/8 octave intervals between 2.1-30 kHz. Exposure frequencies were in the range 3k-20 kHz; exposure levels ranged from 85-120 dB; and durations ranged from 0.5 to 20 min. Regardless of exposure frequency or intensity, the maximum depression of AP occurred at 1/2 octave above the exposure frequency. In addition, recovery was observed over intervals as long as several hours and was found to be slowest at the half-octave above the exposure. The implications for mechanical events underlying cochlear transduction and fatigue will be discussed. [Supported by NINCDS.] [ABSTRACT FROM AUTHOR] |
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