التفاصيل البيبلوغرافية
| العنوان: |
The role of viruses in carcinogenesis. |
| المؤلفون: |
Boon, Virginia, Carr, Jill, Klebe, Sonja |
| المصدر: |
Australian Medical Student Journal; 2013, Vol. 4 Issue 2, p11-15, 5p |
| مصطلحات موضوعية: |
VIRAL carcinogenesis, CARCINOGENESIS, VIRUSES, INFECTION, CARCINOGENICITY |
| مستخلص: |
It is accepted that populations in the so-called developed world have gone through an 'epidemiological transition' where chronic disease has replaced infection as the primary cause of death. However, there is mounting evidence that infections play a key role in certain chronic diseases such as cancer. Cancers of infectious origin provide the perfect opportunity for harnessing the advances that have been made in the control of communicable diseases to attempt the control of noncommunicable diseases. Worldwide, one in every five malignancies can be attributed to infections: this figure is considered conservative and expected to rise. About two-thirds of these cancers occur in less developed countries. The majority of these malignancies are recognised to be caused by viruses via mechanisms of chronic inflammation, immunosuppression or the expression of oncogenic proteins. An understanding of virally mediated carcinogenesis may provide new targets for the development of specified viral therapy that not only impacts on viral infections but human cancer as well. From a public health perspective, viral carcinogenesis is important because it shows potential for preventative and therapeutic programmes to reduce the burden of cancer, particularly in less developed countries. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
