دورية أكاديمية

Familial perimesencephalic subarachnoid hemorrhage: two case reports.

التفاصيل البيبلوغرافية
العنوان: Familial perimesencephalic subarachnoid hemorrhage: two case reports.
المؤلفون: Cıkla, Ulaş, Aagaard-Kienitz, Beverly, Turski, Patrick A., Menekse, Guner, Niemann, David B., Başkaya, Mustafa K.
المصدر: Journal of Medical Case Reports; 2014, Vol. 8 Issue 1, p1-14, 14p
مصطلحات موضوعية: SUBARACHNOID hemorrhage, DISEASE susceptibility, FAMILIAL diseases, DIPLOPIA, CAUCASIAN race, DISEASES
مستخلص: Introduction Non-aneurysmal spontaneous subarachnoid hemorrhage is characterized by an accumulation of a limited amount of subarachnoid hemorrhage, predominantly around the midbrain, and a lack of blood in the brain parenchyma or ventricular system. It represents 5% of all spontaneous subarachnoid hemorrhage cases. In spite of extensive investigation, understanding of the mechanisms leading to perimesencephalic non-aneurysmal subarachnoid hemorrhage remains incompletely defined. A growing body of evidence has supported a familial predisposition for non-aneurysmal spontaneous subarachnoid hemorrhage. Case presentation A 39-year-old Caucasian man presented with sudden onset headache associated with diplopia. His computed tomography scan revealed perimesencephalic subarachnoid hemorrhage. A cerebral angiogram showed no apparent source of bleeding. He was treated conservatively and discharged after 1 week without any neurological deficits. The older brother of the first case, a 44-year-old Caucasian man, presented 1.5 years later with acute onset of headache and his computed tomography scan also showed perimesencephalic nonaneurysmal subarachnoid hemorrhage. He was discharged home with normal neurological examination 1 week later. Follow-up angiograms did not reveal any source of bleeding in either patient. Conclusions We report the cases of two siblings with perimesencephalic non-aneurysmal subarachnoid hemorrhage, which may further suggest a familial predisposition of non-aneurysmal spontaneous subarachnoid hemorrhage and may also point out the possible higher risk of perimesencephalic non-aneurysmal subarachnoid hemorrhage in the first-degree relatives of patients with perimesencephalic non-aneurysmal subarachnoid hemorrhage. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:17521947
DOI:10.1186/1752-1947-8-380