دورية أكاديمية

A rare presentation and recurrence of a retroperitoneal Müllerian cyst in a male patient: A case report.

التفاصيل البيبلوغرافية
العنوان: A rare presentation and recurrence of a retroperitoneal Müllerian cyst in a male patient: A case report.
المؤلفون: Naem, Antoine, Dlewati, Ammar, Alhimyar, Maryam, Ousta, Mohamad Ali, Alsaid, Bayan
المصدر: International Journal of Surgery Case Reports; 2019, Vol. 65, p301-304, 4p
مستخلص: • The Müllerian cyst incidence in males is rare but quiet possible. • The pathological and immunohistochemical examination is essential for the diagnosis. • The immunopositivity for WT1 plays a great role in explaining the cyst's behavior. • Applying the total surgical resection is mandatory in preventing the recurrence. • Chemotherapy can minimize the recurrence and improve the patient's life quality. The retroperitoneal Müllerian cysts are extremely rare lesions seen mostly in female patients but their occurrence in males is quite possible. Their exact etiology stills unknown, its histological and immunohistochemical characteristics may serve as an evidence that reflects its origin. We present a case of a resected retroperitoneal Müllerian cyst that reoccurred severely after 3 months of the first laparotomy in a male patient with a significant history of testicular teratocarcinoma. Due to the cyst's localization and its proximity to vital retroperitoneal structures, total surgical resection couldn't be made and the recurrence was minimized by post-operative oral chemotherapy. The retroperitoneal Müllerian cyst is a benign cystadenoma that could be confused with other retroperitoneal lesions, which makes the pathological examination with the immunohistochemical study of the cyst's wall essential to make the diagnosis. The immunopositivity to Cytokeratin 7 and the immunonegativity to Cytokeratin 20 is a key feature that confirm the diagnosis whenever the retroperitoneal Müllerian cyst is suspected. Due to its high vascularity, we highly recommend the administration of chemotherapy which targets the proliferative cyst's cells. The RMCs are rare benign lesions that tend to reoccur if total surgical resection isn't made, when the total resection couldn't be achieved, the-unspecific anti-mitotic drugs may help in minimizing the recurrence and improve the life quality of the patient. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Supplemental Index
الوصف
تدمد:22102612
DOI:10.1016/j.ijscr.2019.11.001