التفاصيل البيبلوغرافية
| العنوان: |
Moderately hypofractionated post-operative radiation therapy for breast cancer: preferences amongst radiation oncologists from countries in Latin America and the Caribbean. |
| المؤلفون: |
Nader Marta, Gustavo, Moraes, Fabio Y., de Oliveira Franco, Rejane Carolina, de Andrade Carvalho, Heloísa, Guimaraes Gouveia, André, de Lima Gössling, Gustavo Cartaxo, Gomes de Jesus, Rafaela, Ferraris, Gustavo, Munoz Schuffenegger, Pablo, Sarria Bardales, Gustavo, Poitevin Chacón, María Adela, Murillo, Raúl, Moreno Sánchez, Luis Ernesto, Gamarra-Cabezas, Elizabeth, Accioly Rosa, Arthur, Fraga da Silva, Maurício, Duarte de Mattos, Marcos, Rezende Morais, Diego Chaves, Guedes de Castro, Douglas, Dal Pra, Alan |
| المصدر: |
Reports of Practical Oncology & Radiotherapy; 2023, Vol. 28 Issue 3, p340-351, 12p |
| مستخلص: |
Background: The safety and effectiveness of moderately hypofractionated post-operative radiation therapy for breast cancer were demonstrated by several trials. This study aimed to evaluate the current patterns of practice and prescription preference about moderately hypofractionated post-operative radiation therapy to assess possible aspects that affect the decision-making process regarding the use of fractionation in breast cancer patients in Latin America and the Caribbean (LAC). We also aimed to identify factors that can restrain the utilization of moderately hypofractionated post-operative radiation therapy for breast cancer. Materials an methods: Radiation oncologists from LAC were invited to contribute to this study. A 38-question survey was used to evaluate their opinions. Results: A total of 173 radiation oncologists from 13 countries answered the questionnaire. The majority of respondents (84.9%) preferred moderately hypofractionated post-operative radiation therapy as their first choice in cases of whole breast irradiation. Whole breast plus regional nodal irradiation, post-mastectomy (chest wall and regional nodal irradiation) without reconstruction, and post-mastectomy (chest wall and regional node irradiation) with reconstruction hypofractionated post-operative radiation therapy was preferred by 72.2% 71.1%, and 53.7% of respondents, respectively. Breast cancer stage, and flap-based breast reconstruction were the factors associated with absolute contraindications for the use of hypofractionated schedules. Conclusion: Even though moderately hypofractionated post-operative radiation therapy for breast cancer is considered a new standard to the vast majority of the patients, its unrestricted application in clinical practice across LAC still faces reluctance. [ABSTRACT FROM AUTHOR] |
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