دورية
Emollient foam in topical drug delivery
العنوان: | Emollient foam in topical drug delivery |
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المؤلفون: | Tamarkin, Dov, Friedman, Doron, Shemer, Avner |
المصدر: | Expert Opinion on Drug Delivery; November 2006, Vol. 3 Issue: 6 p799-807, 9p |
مستخلص: | Foams offer an innovative and more convenient means of topical drug delivery. The successful introduction of hydroalcoholic foams paved the way for the development of a new generation of foam products that provide skin barrier build-up and hydration. Such foams, designated as emollient foams consist of oil-in-water or water-in-oil emulsions with necessary excipients, such as non-ionic surfactants, gelling agents and foam adjuvants. Emollient foams can carry a broad variety of topical drugs, including water-soluble, oil-soluble and suspended active agents. This paper reviews emollient foam compositions and their physicochemical properties. It further accounts for the usability and functional advantages of emollient foam as a vehicle of topical drugs, including: i) improved usability, which affects treatment, compliance and, consequently, improves therapeutic results; ii) safety; iii) controllable drug delivery; iv) skin barrier build-up and hydration; and v) enhanced clinical efficacy. |
قاعدة البيانات: | Supplemental Index |
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