دورية
Amino acid arterial concentration and muscle exchange during submaximal arm and leg exercise: The effect of dihydroxyacetone and pyruvate
العنوان: | Amino acid arterial concentration and muscle exchange during submaximal arm and leg exercise: The effect of dihydroxyacetone and pyruvate |
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المؤلفون: | Stanko, R. T., Diven, W. F., Robertson, R. J., Spina, R. J., Galbreath, R. W., Reilly, J. J., Goss, F. L. |
المصدر: | Journal of Sports Sciences; February 1993, Vol. 11 Issue: 1 p17-23, 7p |
مستخلص: | The mixture of dihydroxyacetone and pyruvate (DHAP) is an ergogenic aid that enhances muscle glucose extraction during prolonged aerobic exercise. In order to evaluate the effect of DHAP on muscle amino acid extraction during exercise, we measured arterial concentration and muscle exchange of amino acids in 18 untrained healthy male subjects (aged 20-30 years) performing dynamic arm (60% VO2 max, n = 9) or leg (70% VO2 max, n = 9) exercise to exhaustion with and without dietary supplementation of DHAP. The subjects consumed diets (146 kJ kg body weight-1 day-1) containing either 100 g polyglucose, Polycose® (placebo, P) or DHAP (3:1, treatment) substituted for a portion of carbohydrate. The two diets were administered in a double-blind, random, crossover order for a 7-day period. At least 7 days separated the dietary protocols. Blood samples were drawn through radial artery and axillary or femoral vein catheters at rest, during exercise and at exhaustion.Arterial alanine concentration increased by 30% during arm exercise and by 50-60% during leg exercise. No other arterial amino acid concentration changed during exercise. At exhaustion, arterial alanine concentration decreased to pre-exercise levels with arm exercise but remained elevated after leg exercise. Despite changes in arterial concentrations of alanine with exercise, muscle exchange of alanine was not altered with exercise. Exercise did not alter muscle exchange of any amino acid. Arterial amino acid concentrations and muscle exchange of amino acids with exercise were similar with or without DHAP feeding.We conclude that consumption of DHAP does not alter arterial concentration or muscle exchange of amino acids during submaximal arm and leg exercise. |
قاعدة البيانات: | Supplemental Index |
تدمد: | 02640414 1466447X |
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DOI: | 10.1080/02640419308729958 |