دورية
Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists
العنوان: | Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists |
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المؤلفون: | Cimetière, Bernard, Dubuffet, Thierry, Muller, Olivier, Descombes, Jean-Jacques, Simonet, Serge, Laubie, Michel, Verbeuren, Tony J., Lavielle, Gilbert |
المصدر: | Bioorganic & Medicinal Chemistry Letters; June 1998, Vol. 8 Issue: 11 p1375-1380, 6p |
مستخلص: | New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886has been identified as an orally active, highly potent antagonist with a very long duration of action in different species. |
قاعدة البيانات: | Supplemental Index |
تدمد: | 0960894X 14643405 |
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DOI: | 10.1016/S0960-894X(98)00220-0 |