AN EXPERIMENTAL STUDY OF GASEOUS HOMEOSTASIS AND THE MAGILL CIRCUIT USING LOW FRESH GAS FLOWS

التفاصيل البيبلوغرافية
العنوان: AN EXPERIMENTAL STUDY OF GASEOUS HOMEOSTASIS AND THE MAGILL CIRCUIT USING LOW FRESH GAS FLOWS
المؤلفون: CONWAY, C. M., DAVIS, F. M., KNIGHT, H. J., LEIGH, J. M., PRESTON, T. D., TENNANT, R.
المصدر: BJA: British Journal of Anaesthesia; May 1976, Vol. 48 Issue: 5 p447-447, 1p
مستخلص: Gas concentrations and ventilation levels have been measured within a conventional Magill circuit when conscious volunteers breathed a non-narcotic gas mixture at varying fresh gas flows. When evidence of rebreathing of alveolar gas was detected, the fresh gas flow was kept constant until a steady state developed. All subjects showed evidence of rebreathing when the fresh gas flow approached the predicted alveolar ventilation levels. A variety of subject-circuit interactions was seen and shown to be precipitated by naturally occurring breath-to-breath variations in ventilation. A single large breath could perturb the system. This could have a temporary effect, when the fresh gas flow was sufficient to wash the increased aliquot of expired carbon dioxide from the circuit. At other times a progressive response occurred as ventilatory stimulation as a result of the increased inspired carbon dioxide concentrations caused alveolar gas to reach the reservoir bag and converted the system behaviour from that of a simple added deadspace to that of a total mixing device. Whilst marked changes occurred commonly in both ventilation and inspired gas concentrations, only slight changes in end-tidal gas concentrations occurred.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00070912
14716771
DOI:10.1093/bja/48.5.447