دورية
SARS-CoV-2 RNA Detected in Vitreous Samples Obtained at Autopsy
| العنوان: | SARS-CoV-2 RNA Detected in Vitreous Samples Obtained at Autopsy |
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| المؤلفون: | Tieger, Marisa, Das Adhikari, Upasana, Mukai, Shizuo, Farcasnu, Mara, Stone, James R., Eliott, Dean, Kim, Leo A., Kwon, Douglas S., Rossin, Elizabeth J. |
| المصدر: | Journal of VitreoRetinal Diseases; May 2022, Vol. 6 Issue: 3 p183-187, 5p |
| مستخلص: | Purpose: This work aims to examine the vitreous of autopsy patients with COVID-19 for the presence of SARS-CoV-2 RNA.Methods: Four deceased patients with COVID-19 had an autopsy at Massachusetts General Hospital. Two control specimens were obtained from patients undergoing retinal detachment repair with negative preoperative polymerase chain reaction (PCR) testing for SARS-CoV-2 RNA. Vitreous specimens were obtained from autopsy patients with COVID-19 after povidone was placed on the ocular surface to decrease the risk of contamination of the vitreous specimen. SARS-CoV-2 RNA for gene N (nucleocapsid) was tested using reverse transcription–PCR.Results: SARS-CoV-2 RNA was detected in the vitreous of 2 of 4 autopsy patients who died from complications of COVID-19.Conclusions: SARS-CoV-2 RNA can penetrate into the vitreous of systemically infected patients, which might present risks to operating room personnel during ophthalmic surgical procedures. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 24741264 24741272 |
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| DOI: | 10.1177/24741264221083408 |