Efficient High-Throughput Discovery of Large Peptidic Hormones and Biomarkers

التفاصيل البيبلوغرافية
العنوان: Efficient High-Throughput Discovery of Large Peptidic Hormones and Biomarkers
المؤلفون: W. Taylor, Steven, L. Andon, Nancy, M. Bilakovics, James, Lowe, Carolyn, R. Hanley, Michael, Pittner, Richard, S. Ghosh, Soumitra
المصدر: Journal of Proteome Research; July 2006, Vol. 5 Issue: 7 p1776-1784, 9p
مستخلص: A novel approach is presented for the simultaneous identification and relative quantification of secreted peptides, particularly those that have been historically difficult to analyze in a concerted manner. Peptides exceeding 60 residues with various degrees of post-translational modification were identified on a liquid chromatographic time scale. The approach demonstrates high efficiency pattern-based recognition analysis of complex neuroendocrine peptide sets and enables rapid identification of biomarkers from biological material.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:15353893
15353907
DOI:10.1021/pr0600982