Effect of simvastatin combined amlodipine besylate on blood rheology and platelet activation in elderly patients with hypertension complicated with hyperlipemia
التفاصيل البيبلوغرافية
العنوان:
Effect of simvastatin combined amlodipine besylate on blood rheology and platelet activation in elderly patients with hypertension complicated with hyperlipemia
Objective: To investigate the effect of simvastatin combined amlodipine besylate on blood rheology and platelet activation in elderly patients with hypertension complicated with hyperlipemia. Methods: A total of 200 elderly patients with hypertension complicated with hyperlipemia were divided into hypertension group (n=64), hyperlipemia group (n=71) and combined (hypertension complicated with hyperlipemia) group (n=65). And alternate period health check-up 100 cases were selected as control group. The hypertension group was treated with amlodipine besylate monotherapy, hyperlipidemia group with simvastatin monotherapy, combined group received simvastatin combined with amlodipine besylate treatment, patients of three groups were treated for 12 weeks. Blood rheology and platelet activation before and after treatment were compared. Results: After treatment, blood pressure was significantly lower than that before treatment in hypertension and combined group (P
