Cough Sensitivity to Several External Triggers is Associated with Multiple Non-respiratory Symptoms
| العنوان: | Cough Sensitivity to Several External Triggers is Associated with Multiple Non-respiratory Symptoms |
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| المؤلفون: | Heikki O. Koskela, Johanna T. Kaulamo, Anne M. Lätti |
| المصدر: | Lung. |
| بيانات النشر: | Springer Science and Business Media LLC, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine |
| الوصف: | Purpose Enhanced responsiveness to external triggers is thought to reflect hypersensitivity of the cough reflex. It may involve an enhanced sensitivity of the afferent nerves in the airways and/or an abnormal processing of the afferent information by the central nervous system (CNS). The CNS processing of cough has been shown to involve the same regions as those in symptom amplification, a phenomenon that often manifests as multiple symptoms. The main purpose of the present study was to define whether the presence of several cough triggers is associated with multiple symptoms. Methods 2131 subjects with current cough responding to two email surveys filled in a comprehensive questionnaire about social background, lifestyle, general health, doctors’ diagnoses and visits, symptoms, and medication. Multiple symptoms was defined as three or more non-respiratory, non-mental symptoms. Results A carefully controlled multiple regression analysis revealed that the number of cough triggers was the only cough characteristic associating with multiple non-respiratory, non-mental symptoms [aOR 1.15 (1.12–1.19) per one trigger, p Conclusion The association between the number of the cough triggers and multiple symptoms suggests that the CNS component of cough hypersensitivity may be a manifestation of non-specific alteration in the CNS interpretation of various body sensations. The number of cough triggers is a repeatable measure of cough sensitivity. |
| تدمد: | 1432-1750 0341-2040 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::0406be048d5e62e61d61cf25a21aedfb https://doi.org/10.1007/s00408-023-00622-w |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........0406be048d5e62e61d61cf25a21aedfb |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14321750 03412040 |
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