Flow-injection chemiluminescence method for the determination of chloramphenicol based on luminol-sodium periodate order-transform second-chemiluminescence reaction
| العنوان: | Flow-injection chemiluminescence method for the determination of chloramphenicol based on luminol-sodium periodate order-transform second-chemiluminescence reaction |
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| المؤلفون: | Ya-Feng Zhuang, Jie-Li Li, Sheng-Nan Zhu, Wei Wei |
| المصدر: | Luminescence. 26:696-702 |
| بيانات النشر: | Wiley, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Detection limit, Flow injection analysis, Chromatography, Sodium periodate, Chloramphenicol, Relative standard deviation, Biophysics, law.invention, Luminol, chemistry.chemical_compound, chemistry, Chemistry (miscellaneous), law, medicine, Luminescence, medicine.drug, Chemiluminescence |
| الوصف: | A new chemiluminescence (CL) reaction was observed when chloramphenicol solution was injected into the mixture after the end of the reaction of alkaline luminol and sodium periodate or sodium periodate was injected into the reaction mixture of chloramphenicol and alkaline luminol. This reaction is described as an order-transform second-chemiluminescence (OTSCL) reaction. The OTSCL method combined with a flow-injection technique was applied to the determination of chloramphenicol. The optimum conditions for the order-transform second-chemiluminescence emission were investigated. A mechanism for OTSCL has been proposed on the basis of the chemiluminescence kinetic characteristics, the UV-visible spectra and the chemiluminescent spectra. Under optimal experimental conditions, the CL response is proportional to the concentration of chloramphenicol over the range 5.0 × 10(-7)-5.0 × 10(-5) mol/L with a correlation coefficient of 0.9969 and a detection limit of 6.0 × 10(-8) mol/L (3σ). The relative standard deviation (RSD) for 11 repeated determinations of 5.0 × 10(-6) mol/L chloramphenicol is 1.7%. The method has been applied to the determination of chloramphenicol in pharmaceutical samples with satisfactory results. |
| تدمد: | 1522-7235 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::0649d42d85efdfae691a125a17fe771f https://doi.org/10.1002/bio.1298 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........0649d42d85efdfae691a125a17fe771f |
| قاعدة البيانات: | OpenAIRE |
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