التفاصيل البيبلوغرافية
| العنوان: |
The outcomes of transcatheter aortic valve replacement in a cohort of patients with end-stage renal disease |
| المؤلفون: |
Jasmina Katinic, Leigh Trautman, Molly Szerlip, Rebeca J. Kim, Jill Rudolph, Morley A. Herbert, Don Creighton, Vasilis Babaliaros, Vinod H. Thourani, Elizabeth K. Walsh, Howard C. Herrmann, Joseph E. Bavaria, Robert Farkas, Michael J. Mack, Raj Makkar, Tarun Chakravarty, Rebecca Letterer, Tokunbo Adeniyi, Joshua Rovin, David L. Brown, Saif Anwaruddin, Kim T. Baio, D. Craig Miller, Elizabeth M. Holper |
| المصدر: |
Catheterization and Cardiovascular Interventions. 87:1314-1321 |
| بيانات النشر: |
Wiley, 2016. |
| سنة النشر: |
2016 |
| مصطلحات موضوعية: |
medicine.medical_specialty, business.industry, medicine.medical_treatment, Retrospective cohort study, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, End stage renal disease, Surgery, 03 medical and health sciences, Stenosis, 0302 clinical medicine, Valve replacement, Aortic valve replacement, Aortic valve stenosis, medicine, Risk of mortality, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, Dialysis |
| الوصف: |
Objectives To examine whether transcatheter aortic valve replacement (TAVR) is a safe and effective treatment option for aortic stenosis in patients with end-stage renal disease (ESRD). Background Patients with ESRD undergoing surgical aortic valve replacement have an operative mortality approaching 20% and a 10-year survival of approximately 12%. We investigated whether TAVR is a more reasonable option. Methods This is a multicenter, retrospective study of all patients with ESRD who underwent TAVR in 8 institutions between 12/2011 and 02/2013. Demographic characteristics, mortality, major, and minor complications were evaluated. Outcomes were stratified by operative approach. Results Forty-three patients with a mean age 76.2 ± 11.0 years and a mean STS predicted risk of mortality of 15.53 ± 8.70% underwent TAVR. Mean duration of dialysis was 45.2 ± 52.3 months (median 29.5 months). Transfemoral (TF) TAVR was performed in 31/43 (72.1%), transapical in 11/43 (25.6%), and transaortic in 1/43 (2.3%). Operative mortality was 14.0% (6/43) with TF mortality 6.5% (2/31) and 33.3% (4/12) in non-TF patients. Six-month mortality was 11/43 (25.6%: 16.1% TF, 50.0% non-TF). Complications included stroke in 2.3% (1/43) and life-threatening or major bleeding in 14.0% (6/43). Discharge to another healthcare facility was 27.0% (10/37). Readmission within 30 days of procedure for any cause was 18.9% (7/37). Conclusions Patients with ESRD who undergo TAVR are at high risk for mortality and complications. TAVR outcomes are comparable to but not substantially better than those with SAVR. Transfemoral TAVR seems to be at least as safe and effective as the current standard SAVR in patients undergoing aortic valve replacement. © 2016 Wiley Periodicals, Inc. |
| تدمد: |
1522-1946 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_________::3acb86edb4cc27bacb76f4542ef71837
https://doi.org/10.1002/ccd.26347 |
| حقوق: |
OPEN |
| رقم الأكسشن: |
edsair.doi...........3acb86edb4cc27bacb76f4542ef71837 |
| قاعدة البيانات: |
OpenAIRE |
