639 A case of acute transient constrictive pericarditis—an unusual presentation

التفاصيل البيبلوغرافية
العنوان: 639 A case of acute transient constrictive pericarditis—an unusual presentation
المؤلفون: Paolo Marco Pietro Spissu, Simone Angius, Maria Francesca Marchetti, Ludovica Caggiari, Alessandra Gioi, Giulia Mura, Martina Mandas, Marco Licciardi, Luigi Meloni, Roberta Montisci
المصدر: European Heart Journal Supplements. 23
بيانات النشر: Oxford University Press (OUP), 2021.
سنة النشر: 2021
مصطلحات موضوعية: cardiovascular system, Cardiology and Cardiovascular Medicine
الوصف: Aims Transient constrictive pericarditis (TCP) is a rare manifestation which can occur in up to 15% of cases of acute pericarditis and most have resolution after 3 months of anti-inflammatory therapy. Methods and results We present the case of a young guy who showed up at our emergency department complaining of pericarditic chest pain and fever up to 39 °C degrees since the previous 4 days. After physical examination, electrocardiogram, blood tests, chest X-ray, and echocardiography acute pericarditis with severe pericardial effusion (more than 20 mm of thickness) were diagnosed and an empiric anti-inflammatory therapy with ibuprofen and colchicine was started. After 2 weeks of therapy, patient was not clinically improving with a worsened pericardial effusion and only a mild reduction of inflammatory markers. During an echocardiographic examination, features of constrictive physiology were discovered: respirophasic interventricular septal shift, increased respiratory variation of the mitral and tricuspidal inflow, plethoric inferior vena cava, and ‘annulus reversus’ and ‘annulus paradoxus’ on Tissue Doppler Imaging (TDI). Cardiac magnetic resonance (CMR) was also performed to confirm the diagnosis of acute pericardial constriction: it revealed increased T2-weighted imaging signal and increased Delayed Gadolinium Enhanced (DGE) signal, respectively consistent with oedema and with neovascularization, both suggestive of acute pericardial inflammation. Therefore, oral low doses corticosteroid was started After 2 weeks course of ‘triple therapy’ the patient was clinically improved and the echocardiographic features of constrictive physiology were no longer present thus allowing his discharge and the continuation of therapy at home. Conclusions This case was remarkable because it showed that constrictive pericarditis may present in a reversible form with medical therapy, this meaning it is due to pericardial oedema, inflammation and fibrin deposition similar to acute pericarditis rather than the pericardial fibrosis and calcification more commonly seen in chronic pericardial constriction.
تدمد: 1554-2815
1520-765X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4bb0f8d64838c535cacbd71184d0d994
https://doi.org/10.1093/eurheartj/suab142.052
حقوق: OPEN
رقم الأكسشن: edsair.doi...........4bb0f8d64838c535cacbd71184d0d994
قاعدة البيانات: OpenAIRE