Factores relacionados con la adherencia en pacientes infectados por el virus de la inmunodeficiencia humana
| العنوان: | Factores relacionados con la adherencia en pacientes infectados por el virus de la inmunodeficiencia humana |
|---|---|
| المؤلفون: | E.M. Andrés Esteban, V. Napal Lecumberri, A. Iruin Sanz, A. Arrondo Velasco, M.L. Sainz Suberviola |
| المصدر: | Farmacia Hospitalaria. 33:4-11 |
| بيانات النشر: | Elsevier BV, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Pharmacology, medicine.medical_specialty, Multivariate analysis, business.industry, Concordance, Pharmacy, Internal medicine, Female patient, medicine, Statistical analysis, Observational study, business, Viral load, Diffi cult |
| الوصف: | Objective: To establish the relationship between the adherence to ARVT and the clinical situation and detect those factors which relate to the lack of adherence. Method: Observational study on HIV patients who had attended the Pharmacy Service in Navarra Hospital between February and May 2005. The SMAQ questionnaire and pharmacy dispensing records were used to assess adherence to treatment. Socio-demographic variables and other factors which could infl uence adherence were recorded. Statistical analysis was carried out using the SPSS programme, version 14.0. Results: No concordance was noted between the two measurements of adherence, although there was an association between the viral load and compliance, irrespective of the method used. The questionnaire recorded a higher percentage of non-adhering female patients, substance users and psychiatric patients. Non-adhering patients indicated more frequently factors which made taking the medication diffi cult. The multivariate analysis showed that the lack of a suitable social-familial environment negatively influenced the adherence level, according to the SMAQ questionnaire, and that the high number of tablets per dose was related to the lack of adherence according to the pharmacy dispensing records. Conclusions: Patients who adhere to ARVT have a lesser risk of virological failure. An unsuitable social-familial environment and the complexity of treatment are associated with a lack of adherence. The method of using dispensing records should be combined with a patient interview to defi ne the factors which reduce adherence and to propose intervention strategies. |
| تدمد: | 1130-6343 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::52e8fd1881d2204cedde1ee882ab7395 https://doi.org/10.1016/s1130-6343(09)70729-9 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........52e8fd1881d2204cedde1ee882ab7395 |
| قاعدة البيانات: | OpenAIRE |
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