Abstract 16583: Beta Blocker Administration Within 30 Days Post-Left Ventricular Assist Device Significantly Decreases 1-Year Mortality in a Multi-institutional Retrospective Cohort Study

التفاصيل البيبلوغرافية
العنوان: Abstract 16583: Beta Blocker Administration Within 30 Days Post-Left Ventricular Assist Device Significantly Decreases 1-Year Mortality in a Multi-institutional Retrospective Cohort Study
المؤلفون: Mercedes Rivas-Lasarte, Daniel B. Sims, Aaron Guo, S. Kumar, Somayya J. Mohammad, Matthew Cefalu, Mohamed H. Derbala, Joel Ferrall, Sakima A. Smith
المصدر: Circulation. 142
بيانات النشر: Ovid Technologies (Wolters Kluwer Health), 2020.
سنة النشر: 2020
مصطلحات موضوعية: business.industry, medicine.drug_class, Physiology (medical), Anesthesia, Ventricular assist device, medicine.medical_treatment, Medicine, Retrospective cohort study, Cardiology and Cardiovascular Medicine, business, 1 year mortality, Beta blocker, Administration (government)
الوصف: Introduction: The utilization of beta blockers (BB) post LVAD implantation is controversial, especially in the setting of right ventricular failure. There is limited evidence-based data regarding the survival benefits of BB post LVAD implantation Hypothesis: We hypothesized that BB use would not be associated with increased mortality Methods: We performed a dual-center retrospective study of 487 patients from Ohio State University & Montefiore Medical Center who received a continuous-flow durable LVAD bet. Jan 2006 through Dec 2016. A survival analysis was done to determine if patients had increased 1 year mortality depending on whether they received BB within 30 days post LVAD, after 30 days & up to 1 year post LVAD, or did not receive BB. Multivariate analysis of predictors of post LVAD mortality was conducted. Results: Overall the baseline characteristics bet. the 3 groups were similar (Table 1). BB utilization within 30 days post LVAD was associated with a drastic decrease in 1 year mortality (p Conclusions: The early use of BB significantly improves 1 year survival post LVAD. Notably these results are from Midwest and East Coast Medical Centers to improve generalizability.
تدمد: 1524-4539
0009-7322
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5540380c4fa02c07458b507b4675d64b
https://doi.org/10.1161/circ.142.suppl_3.16583
رقم الأكسشن: edsair.doi...........5540380c4fa02c07458b507b4675d64b
قاعدة البيانات: OpenAIRE