Animal models for rotator cuff repair

التفاصيل البيبلوغرافية
العنوان: Animal models for rotator cuff repair
المؤلفون: Christopher L. Camp, Amir Lebaschi, Xiang-Hua Deng, Zoe Album, Scott A. Rodeo, Camila B. Carballo, Guang-Ting Cong, Jianchun Zong
المصدر: Annals of the New York Academy of Sciences. 1383:43-57
بيانات النشر: Wiley, 2016.
سنة النشر: 2016
مصطلحات موضوعية: 030222 orthopedics, medicine.medical_specialty, Functional impairment, business.industry, General Neuroscience, 030229 sport sciences, Surgical procedures, General Biochemistry, Genetics and Molecular Biology, Surgery, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, History and Philosophy of Science, Murine model, Small animal, Medicine, Rotator cuff, business, Neuroscience
الوصف: Rotator cuff (RC) injuries represent a significant source of pain, functional impairment, and morbidity. The large disease burden of RC pathologies necessitates rapid development of research methodologies to treat these conditions. Given their ability to model anatomic, biomechanical, cellular, and molecular aspects of the human RC, animal models have played an indispensable role in reducing injury burden and advancing this field of research for many years. The development of animal models in the musculoskeletal (MSK) research arena is uniquely different from that in other fields in that the similarity of macrostructures and functions is as critical to replicate as cellular and molecular functions. Traditionally, larger animals have been used because of their anatomic similarity to humans and the ease of carrying out realistic surgical procedures. However, refinement of current molecular methods, introduction of novel research tools, and advancements in microsurgical techniques have increased the applicability of small animal models in MSK research. In this paper, we review RC animal models and emphasize a murine model that may serve as a valuable instrument for future RC tendon repair investigations.
تدمد: 0077-8923
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::92717211aaca8a4d76ec427b269443a2
https://doi.org/10.1111/nyas.13203
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........92717211aaca8a4d76ec427b269443a2
قاعدة البيانات: OpenAIRE