The amidiniohydrazone group of the title compound (5-acetyl-4-methyl-2-methylthiopyrimidine amidinohydrazone dihydrochloride) has a trans conformation (E) and the (amidiniohydrazone)ethyl part of the molecule compares very well with the same chaining in mitoguazone and its analogue. Both ionic salts are stabilized by a series of hydrogen bonds to both water molecules and chlorine ions. The structure consists of stacks of parallel planes of the dipositive ion