Stereotactic radiosurgery for orbital cavernous hemangiomas
| العنوان: | Stereotactic radiosurgery for orbital cavernous hemangiomas |
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| المؤلفون: | You-Cong Chen, Chieh-Chih Tsai, Shih-Jen Chen, Hsiu-Mei Wu, Huai-Che Yang, Ching-Jen Chen, Yong-Sin Hu, Chung-Jung Lin, Wan-Yuo Guo, David Hung-Chi Pan, Wen-Yuh Chung, Cheng-Chia Lee |
| المصدر: | Journal of Neurosurgery. :1-8 |
| بيانات النشر: | Journal of Neurosurgery Publishing Group (JNSPG), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | General Medicine |
| الوصف: | OBJECTIVE The goal of this study was to assess the safety and efficacy of single-session Gamma Knife radiosurgery (GKRS) for orbital cavernous hemangiomas (OCHs). METHODS Patients who presented with an OCH between September 1999 and May 2022 and were treated with single-session GKRS were included in this single-center cohort study. RESULTS There were 23 patients (7 males and 16 females) in this study. The median margin dose was 12 Gy (range 11–13 Gy). The median clinical and radiological follow-ups were 45 months (range 5–190 months) and 45 months (range 6–190 months), respectively. Nine (69.2%) of 13 patients with visual acuity impairment had improvement in best corrected visual acuity. Of the 8 patients with visual field defects, 5 patients (62.5%) had complete resolution. Tumor regression was observed in 22 patients (95.7%). The mean relative reduction in tumor volume was 82.6% ± 23.7%. The relative reductions in tumor volume were 33%, 49%, 72%, 84%, and 89% at 6, 12, 24, 36, and 48 months, respectively. Adverse effects of radiation were not observed. CONCLUSIONS GKRS appears to be safe and efficacious for treating OCHs over long-term follow-up. The treatment is associated with a high rate of regression in OCHs and remarkable improvement in both visual acuity and visual field deficits. |
| تدمد: | 1933-0693 0022-3085 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::a6a5b2b5c2ae73938673657a012b620e https://doi.org/10.3171/2022.8.jns221222 |
| رقم الأكسشن: | edsair.doi...........a6a5b2b5c2ae73938673657a012b620e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19330693 00223085 |
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