Feasibility Study for the Long-Term Management of Refractory Hyperkeratotic Eczema with Calcipotriol and Betamethasone Dipropionate (Daivobet®), Viaminate and Concomitant Conventional Therapies: A Retrospective Study
العنوان: | Feasibility Study for the Long-Term Management of Refractory Hyperkeratotic Eczema with Calcipotriol and Betamethasone Dipropionate (Daivobet®), Viaminate and Concomitant Conventional Therapies: A Retrospective Study |
---|---|
المؤلفون: | Amelia Nabatanzi, Chunxia Tian, Lingyun Zhang, Ting Wu, Musa Male, Magesa Mafuru, Shidi Wu, Changzheng Huang |
المصدر: | Clinical, Cosmetic and Investigational Dermatology. 13:789-794 |
بيانات النشر: | Informa UK Limited, 2020. |
سنة النشر: | 2020 |
مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Betamethasone dipropionate, Retrospective cohort study, Dermatology, Single Center, Occlusive dressing, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Refractory, chemistry, 030220 oncology & carcinogenesis, Concomitant, Post-hoc analysis, medicine, business, Calcipotriol, medicine.drug |
الوصف: | Background The available treatments for refractory hyperkeratotic eczema are inadequate with frustrating results. We, therefore, incorporated Calcipotriol and Betamethasone Dipropionate (Daivobet®), and Viaminate into the mainstay treatment to improve the clinical symptoms. The study aimed to evaluate the efficacy of Daivobet ® and Viaminate as a potential treatment alternative for refractory hyperkeratotic eczema. Patients and Methods Between 2013 and 2015, 61 patients diagnosed with refractory hyperkeratotic eczema (RHE) who had shown inadequate response to conventional therapies were pooled from a single center. Besides, they were all treated with Daivobet ® , Viaminate, and an occlusive dressing mixture containing 5% salicylic acid ointment and 25% zinc oxide paste following inadequate response to conventional therapies (corticosteroids plus 25% zinc oxide paste and 5% salicylic acid ointment). Investigators Global Assessment (IGA) and Patient-Oriented Eczema Measure (POEM) assessed baseline and outcome measures for the degree of hyperkeratinization (0-clear; 3-moderate; 4-severe). Results Of the 61 patients, 49 (80.3%) patients presented with moderate RHE and 12 (19.7%) with severe RHE. After 24 weeks of treatment, the period for loss of keratinization was significantly lower in patients with moderate RHE (3.9±1.9 weeks) than those with severe RHE (10.8±1.0 weeks) with a P-value |
تدمد: | 1178-7015 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ce27bd183576f621e982201756695b02 https://doi.org/10.2147/ccid.s276148 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi...........ce27bd183576f621e982201756695b02 |
قاعدة البيانات: | OpenAIRE |
كن أول من يترك تعليقا!