Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and morphologic MRI of cartilage in the long-term follow-up after Legg-Calvé-Perthes disease (LCPD)
العنوان: | Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and morphologic MRI of cartilage in the long-term follow-up after Legg-Calvé-Perthes disease (LCPD) |
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المؤلفون: | Gerald Antoch, Tanja Haamberg, Dirk Blondin, G. Fürst, Tallal C. Mamisch, Bernd Bittersohl, Rotem S. Lanzman, Arne Holstein, Christoph Zilkens, Patric Kröpil, Rüdiger Krauspe, Falk Miese, Marcus Jäger |
المصدر: | Journal of Medical Imaging and Radiation Oncology. 55:259-265 |
بيانات النشر: | Wiley, 2011. |
سنة النشر: | 2011 |
مصطلحات موضوعية: | medicine.medical_specialty, medicine.diagnostic_test, Long term follow up, business.industry, Gadolinium, Cartilage, chemistry.chemical_element, Magnetic resonance imaging, medicine.disease, Acetabular cartilage, medicine.anatomical_structure, Oncology, chemistry, medicine, Legg-Calve-Perthes disease, Radiology, Nuclear Medicine and imaging, Femur, Radiology, business, Pelvis |
الوصف: | Introduction: The purpose of the present study was to evaluate the feasibility of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) in the detection of cartilage changes versus morphologic imaging in the long-term course of Legg–Calve–Perthes disease (LCPD). Methods: A total of 31 hips in 26 patients (mean age, 30.0 years; range, 18–54 years) who were diagnosed with LCPD in childhood were included. Twenty-one radiographically normal contralateral hips served as controls. dGEMRIC indices of femoral and acetabular cartilage in the weight-bearing zone. Cartilage morphology was classified on radial PD-weighted images according to the modified Outerbridge classification. Results: Mean dGEMRIC values of cartilage were significantly lower in hips after LCPD than in the radiographically normal contralateral hips (513 ± 100 ms vs. 579 ± 103 ms; P = 0.026). In 24 out of 31 LCPD hips and in 4 out of 21 radiographically normal contralateral hips, morphological cartilage changes were noted. Analysis of variance analysis revealed a significant influence of Outerbridge grading on decreased T1-values (P = 0.031). Conclusion: Our results suggest that dGEMRIC at 1.5 T is suitable to assess cartilage quality changes in the long-term follow-up after LCPD. The evaluation of biochemical cartilage quality with dGEMRIC may provide additional information about early cartilage changes occurring without visible alterations of cartilage morphology. |
تدمد: | 1754-9477 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::dfb810aef66278028e99ff9e3aae3178 https://doi.org/10.1111/j.1754-9485.2011.02262.x |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi...........dfb810aef66278028e99ff9e3aae3178 |
قاعدة البيانات: | OpenAIRE |
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