Supplementary Table S1 and Figures S1-S7 from ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
التفاصيل البيبلوغرافية
العنوان:
Supplementary Table S1 and Figures S1-S7 from ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
American Association for Cancer Research (AACR), 2023.
سنة النشر:
2023
الوصف:
Supplementary table S1 shows the effect of ODM-203 in a large kinase panel. Supplementary figure S1 shows how ODM-203 is synthesized. Supplementary figure S2 shows the effect of ODM-203 on FRS2 phosphorylation. Supplement figure S3 shows the effect of ODM-203 in additional in vivo xenograft models. Supplement figure S4 shows the effect of ODM-203 on pFGFR in the SNU16 xenograft model. Supplement figure S5 shows the effect of ODM-203 on pFGFR in the KSM11 xenograft model. Supplement figure S6 shows the effect of ODM-203 angiogenesis in vivo. Supplement figure S7 shows the effect of ODM-203 on PD-L1 expression in vitro.