Diagnostic Value of Contrast-Enhanced Spectral Mammography in Comparison to Magnetic Resonance Imaging in Breast Lesions

التفاصيل البيبلوغرافية
العنوان: Diagnostic Value of Contrast-Enhanced Spectral Mammography in Comparison to Magnetic Resonance Imaging in Breast Lesions
المؤلفون: Cuijuan Hao, Qianqian Chen, Bolin Sun, Dong Xing, Xiaoxiao Chi, Haizhu Xie, Jianjun Dong, Yongbin Lv
المصدر: Journal of Computer Assisted Tomography
بيانات النشر: Lippincott Williams & Wilkins, 2018.
سنة النشر: 2018
مصطلحات موضوعية: Adult, medicine.medical_specialty, Contrast Media, Physical examination, Breast Neoplasms, Sensitivity and Specificity, 030218 nuclear medicine & medical imaging, Diagnosis, Differential, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, breast cancer, medicine, Mammography, Humans, Radiology, Nuclear Medicine and imaging, Breast, Aged, Contrast enhanced spectral mammography, Aged, 80 and over, medicine.diagnostic_test, Receiver operating characteristic, business.industry, Breast Imaging, Magnetic resonance imaging, contrast agent, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Radiographic Image Enhancement, Histopathology, Female, Breast disease, business, Nuclear medicine, contrast-enhanced spectral mammography, 030217 neurology & neurosurgery
الوصف: Objective The aim of this study was to evaluate the diagnostic value between contrast-enhanced spectral mammography (CESM) and breast magnetic resonance imaging (MRI) in breast disease. Methods Two hundred thirty-five patients who were suspected of having breast abnormalities by clinical examination or mammography underwent CESM and MRI examination. Using histopathologic results as the criterion standard, the diagnostic performance of CESM and MRI was investigated. The areas under receiver operating characteristic curves were applied to analyze diagnostic efficiency. The Pearson correlation coefficients between CESM versus pathology and MRI versus pathology were calculated. Results Two hundred sixty-three breast lesions were found in 235 patients, in which 177 were malignant and 86 were benign. By evaluating the diagnostic value, sensitivity, positive predictive value, negative predictive value, and false-negative rate from CESM examination were comparable to those from MRI (91.5%, 94.7%, 83.7%, and 8.5% vs 91.5%, 90.5%, 82.1%, and 8.5%). Importantly, the accuracy and the specificity were higher for CESM than those for MRI (81% and 89.5% vs 80.2% and 71.7%), whereas the false-positive rate was lower (10.5% vs 19.8%). The areas under receiver operating characteristic curves of CESM and MRI were 0.950 and 0.939, displaying the equivalent diagnostic efficiency (P = 0.48).For the agreement between measurements, mean tumor sizes were 3.1 cm for CESM and 3.4 cm for MRI compared with 3.2 cm on histopathologic results. The Pearson correlation coefficient of CESM versus histopathology (r = 0.774, P = 0.000) was consistent with MRI versus histopathology (r = 0.771, P = 0.000). Conclusions Our results show better accuracy, specificity, and false-positive rate of CESM in breast cancer detection than MRI. Contrast-enhanced spectral mammography displayed a good correlation with histopathology in assessing the lesion size of breast cancer, which is consistent with MRI.
اللغة: English
تدمد: 1532-3145
0363-8715
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0464a7dda51b34f2a5b30e507ab5eb11
http://europepmc.org/articles/PMC6426358
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....0464a7dda51b34f2a5b30e507ab5eb11
قاعدة البيانات: OpenAIRE