Successful treatment of the face post acne erythema using a topically applied selective alpha 1-Adrenergic receptor agonist, oxymetazoline 1.5%, a controlled left to right face comparative trial
| العنوان: | Successful treatment of the face post acne erythema using a topically applied selective alpha 1-Adrenergic receptor agonist, oxymetazoline 1.5%, a controlled left to right face comparative trial |
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| المؤلفون: | Naglaa Agamia, Amira B Kassem, Marwa M. Essawy |
| المصدر: | Journal of Dermatological Treatment. 33:904-909 |
| بيانات النشر: | Informa UK Limited, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Agonist, medicine.medical_specialty, animal structures, Erythema, medicine.drug_class, Administration, Topical, Oxymetazoline, Inflammation, Dermatology, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Acne Vulgaris, medicine, Humans, skin and connective tissue diseases, Acne, Alpha-1 adrenergic receptor, 030203 arthritis & rheumatology, integumentary system, business.industry, Comparative trial, medicine.disease, Treatment Outcome, Face, embryonic structures, medicine.symptom, business, Adrenergic alpha-Agonists, medicine.drug |
| الوصف: | Post-inflammatory erythema (PIE) is a common sequalae of acne inflammation, persistent post acne erythema (PAE) is cosmetically unacceptable and sometimes its complete clearance could not be achieved. Oxymetazoline (OXZ) is a synthetic, direct-acting, sympathomimetic agonist that is highly selective for the 1α-adrenoceptor. It is a potent vasoconstrictor and well known for its ability to clinically 'get the red out'.The aim of this study was to evaluate the efficacy and safety of topical oxymetazoline (OXZ) 1.5% in treatment of post acne erythema (PAE) in a left to right face comparative study.This study was conducted on 40 patients diagnosed with post acne erythema for at least 3 months, the left side of the face was treated with topical OXZ 1.5% in liposomal base and was compared to the right side to which topical lipogel was applied as a control.According to the investigator's global assessment of photographs and the analysis of erythema with image analysis software, topical OXZ was significantly effective in diminishing PAE when compared to topical placebo lipogel.Topical OXZ is a safe and effective treatment for post-acne erythema. |
| تدمد: | 1471-1753 0954-6634 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0532a1037232a33ae05fbaee1da7dc52 https://doi.org/10.1080/09546634.2020.1789045 |
| رقم الأكسشن: | edsair.doi.dedup.....0532a1037232a33ae05fbaee1da7dc52 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 14711753 09546634 |
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