Studies on the pathogenicity of enterovirus-like viruses in chickens
| العنوان: | Studies on the pathogenicity of enterovirus-like viruses in chickens |
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| المؤلفون: | V. Calvert, D A Moffet, J. A. Smyth, Francis McNeilly, T. J. Connor, M S McNulty |
| المصدر: | Avian Pathology. 36:119-126 |
| بيانات النشر: | Informa UK Limited, 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Gastrointestinal Diseases, viruses, Kidney, medicine.disease_cause, Virus, Astrovirus, Microbiology, Food Animals, Antigen, Enterovirus Infections, medicine, Animals, Antigens, Viral, Lung, Poultry Diseases, Enterovirus, Specific-pathogen-free, General Immunology and Microbiology, biology, biology.organism_classification, Virology, Specific Pathogen-Free Organisms, Gastrointestinal Tract, Tissue tropism, biology.protein, Animal Science and Zoology, Flock, Antibody, Chickens, Spleen |
| الوصف: | FP3 and 612 viruses are enterovirus-like viruses. Antibody to these viruses is widespread in chicken flocks, but nothing is known about their pathogenicity. Seven experiments were carried out to investigate the tissue tropism and associated pathology of these novel fowl enterovirus-like viruses and to compare these with the effects of the previously studied enterovirus-like viruses, ELV-1 and avian nephritis (ANV). ANV is now classified as an astrovirus. Preliminary experiments were carried out with FP3 virus, 612 virus and ELV-1 to determine the distribution of viral antigen. Each preliminary experiment was followed by a larger experiment that included more birds and in which a greater range of tissues was studied. It was shown that all four viruses studied replicated in the intestine and had differing abilities to spread to other tissues. Histological changes were present in most antigen-positive tissues but they were usually relatively mild. ELV-1 was associated with the most severe intestinal lesions, followed by FP3 virus. FP3 virus produced lesions in the kidney that were marginally more severe than those caused by the G-4260 strain of ANV. FP3 virus also caused pancreatic lesions. The 612 virus was found to be only mildly pathogenic in specific pathogen free chickens. |
| تدمد: | 1465-3338 0307-9457 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064e62643cb25d13ec67356e8a2b9b57 https://doi.org/10.1080/03079450601161398 |
| رقم الأكسشن: | edsair.doi.dedup.....064e62643cb25d13ec67356e8a2b9b57 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 14653338 03079457 |
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