Validation of a Monte Carlo simulation of the Philips Allegro/GEMINI PET systems using GATE
| العنوان: | Validation of a Monte Carlo simulation of the Philips Allegro/GEMINI PET systems using GATE |
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| المؤلفون: | A. Turzo, Yves Bizais, C. Cheze Le Rest, Dimitris Visvikis, F. Lamare |
| المصدر: | Physics in Medicine and Biology. 51:943-962 |
| بيانات النشر: | IOP Publishing, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Physics, Scanner, Radiological and Ultrasound Technology, Image quality, Software Validation, Monte Carlo method, Whole body imaging, Reproducibility of Results, Equipment Design, Dead time, Radiation Dosage, Models, Biological, Sensitivity and Specificity, Coincidence, Equipment Failure Analysis, Positron-Emission Tomography, Humans, Computer Simulation, Radiology, Nuclear Medicine and imaging, Sensitivity (control systems), Radiometry, Monte Carlo Method, Image resolution, Software, Simulation |
| الوصف: | A newly developed simulation toolkit, GATE (Geant4 Application for Tomographic Emission), was used to develop a Monte Carlo simulation of a fully three-dimensional (3D) clinical PET scanner. The Philips Allegro/GEMINI PET systems were simulated in order to (a) allow a detailed study of the parameters affecting the system's performance under various imaging conditions, (b) study the optimization and quantitative accuracy of emission acquisition protocols for dynamic and static imaging, and (c) further validate the potential of GATE for the simulation of clinical PET systems. A model of the detection system and its geometry was developed. The accuracy of the developed detection model was tested through the comparison of simulated and measured results obtained with the Allegro/GEMINI systems for a number of NEMA NU2-2001 performance protocols including spatial resolution, sensitivity and scatter fraction. In addition, an approximate model of the system's dead time at the level of detected single events and coincidences was developed in an attempt to simulate the count rate related performance characteristics of the scanner. The developed dead-time model was assessed under different imaging conditions using the count rate loss and noise equivalent count rates performance protocols of standard and modified NEMA NU2-2001 (whole body imaging conditions) and NEMA NU2-1994 (brain imaging conditions) comparing simulated with experimental measurements obtained with the Allegro/GEMINI PET systems. Finally, a reconstructed image quality protocol was used to assess the overall performance of the developed model. An agreement of |
| تدمد: | 1361-6560 0031-9155 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abe230020e8dd7ea0a319482877a540 https://doi.org/10.1088/0031-9155/51/4/013 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0abe230020e8dd7ea0a319482877a540 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13616560 00319155 |
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