Endoscopic ultrasound gives high resolution images of the mediastinum and abdominal organ and improves visualization for obtaining tissue sample for cytology. In our study 112 subjects underwent EUS guided FNAC, out of them 51 were diagnosed as carcinoma (45.5%), 15 as tuberculosis (13.39%), reactive adenitis is 13 (11.6%), other benign disease is 27 (24.1%). So overall diagnosis we made in (106/112) (94.6%). 6 (5.3%) were inconclusive. We suggest that EUSFNAC should be the first line investigation for suspected mediastinal and intra-abdominal malignant masses.
