Nighttime Awakenings Responding to Gabapentin Therapy in Late Premenopausal Women: A Case Series
| العنوان: | Nighttime Awakenings Responding to Gabapentin Therapy in Late Premenopausal Women: A Case Series |
|---|---|
| المؤلفون: | Thomas Guttuso |
| المصدر: | Journal of Clinical Sleep Medicine. :187-189 |
| بيانات النشر: | American Academy of Sleep Medicine (AASM), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Pulmonary and Respiratory Medicine, Departments, Cyclohexanecarboxylic Acids, Gabapentin, Physiology, Sweating, Bedtime, Follicle-stimulating hormone, Hot flash, Sleep Initiation and Maintenance Disorders, mental disorders, medicine, Humans, Amines, Low serum estradiol, gamma-Aminobutyric Acid, Estradiol, Luteinizing Hormone, Middle Aged, medicine.disease, Menopause, Anti-Anxiety Agents, Premenopause, Neurology, Anesthesia, Etiology, Female, Neurology (clinical), Follicle Stimulating Hormone, medicine.symptom, Psychology, Luteinizing hormone, psychological phenomena and processes, medicine.drug |
| الوصف: | Insomnia related to nighttime awakenings is known to be more prevalent in women than men. Three cases are presented here of late premenopausal women experiencing frequent nighttime awakenings that responded well to bedtime treatment with gabapentin. In one case, what started as isolated nighttime awakenings slowly progressed to awakenings accompanied by typical menopausal night sweats. This led to the theory that the initial isolated nighttime awakenings in this patient may have been secondary to a menopausal etiology related to low serum estradiol levels. In the subsequent 2 cases, early follicular phase serum estradiol was confirmed to be low. It is theorized that isolated nighttime awakenings in some premenopausal women may be caused by low serum estradiol, triggering events physiologically related to menopausal night sweats. Further research is needed to determine if low early follicular phase serum estradiol is associated with nighttime awakenings in premenopausal women not experiencing night sweats. |
| تدمد: | 1550-9397 1550-9389 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f995f52a0cac500d6e111504f422ef0 https://doi.org/10.5664/jcsm.1776 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0f995f52a0cac500d6e111504f422ef0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15509397 15509389 |
|---|