A novel picornavirus, turkey avisivirus (TuASV), was identified from the feces of turkeys ( Meleagris gallopavo ) with gastrointestinal disease from a farm in Indiana. Its genome organization is as follows: 5′ untranslated region (UTR) IRES-II [VP0, VP3, VP1, 2A, 2B, 2C, 3A, 3B, 3C pro , 3D pol ] 3′ UTR-poly(A). TuASV shares only 34% (P1), 36% (P2), and 35% (P3) amino acid identities with avihepatoviruses, indicating that it potentially represents a novel picornavirus genus.
