PH1-Positive Chronic Myelogenous Leukemia, with Absence of Another G Chromosome, in a Male
العنوان: | PH1-Positive Chronic Myelogenous Leukemia, with Absence of Another G Chromosome, in a Male |
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المؤلفون: | Engel E, Jenkins De, Engel-de Montmollin M, McGee Bj, R. E. Tipton |
المصدر: | New England Journal of Medicine. 273:738-742 |
بيانات النشر: | Massachusetts Medical Society, 1965. |
سنة النشر: | 1965 |
مصطلحات موضوعية: | Chromosome Aberrations, Male, Blood Cells, Autosome, business.industry, G chromosome, Chromosome, Bone Marrow Cells, Chromosome Disorders, General Medicine, Middle Aged, medicine.disease, Y chromosome, Ph1 positive chronic myelogenous leukemia, Myelogenous, Bone Marrow, Leukemia, Myeloid, Centromere, Immunology, medicine, Humans, business, Skin, Chronic myelogenous leukemia |
الوصف: | ALTERATIONS of smaller acrocentric chromosomes in malignant blood diseases have drawn much attention ever since the Philadelphia (PH1) chromosome was noted in chronic myelogenous leukemia.1 , 2 In 1962 Atkin and Taylor3 described a fifty-three-year-old male patient with untreated chronic myelogenous leukemia whose blood cells had the PH1 chromosome but also lacked a short acrocentric chromosome in the G group, either an autosome or the Y chromosome. In 2 other cases in males Tough et al.4 observed a similar pattern: in 1 patient, lack of a G group member was found in all cells with the PH1 chromosome whereas in the . . . |
تدمد: | 1533-4406 0028-4793 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108df62fcf3b3046ed5bc4f72170c67f https://doi.org/10.1056/nejm196509302731404 |
رقم الأكسشن: | edsair.doi.dedup.....108df62fcf3b3046ed5bc4f72170c67f |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15334406 00284793 |
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