Opinion controversy to chromium picolinate therapy’s safety and efficacy: ignoring ‘anecdotes’ of case reports or recognising individual risks and new guidelines urgency to introduce innovation by predictive diagnostics?
| العنوان: | Opinion controversy to chromium picolinate therapy’s safety and efficacy: ignoring ‘anecdotes’ of case reports or recognising individual risks and new guidelines urgency to introduce innovation by predictive diagnostics? |
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| المؤلفون: | Kristina Yeghiazaryan, Olga Golubnitschaja |
| المصدر: | The EPMA Journal |
| بيانات النشر: | BioMed Central, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | medicine.medical_specialty, medicine.medical_treatment, Pre/diabetes care, Alternative medicine, Predictive preventive personalised medicine, Individual profiles, Therapy response, Review, Bioinformatics, Subcellular imaging patterns, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Drug Discovery, medicine, Integrative medicine, Intensive care medicine, 030304 developmental biology, Patient records, 0303 health sciences, biology, business.industry, Athletes, Health Policy, Insulin, Biochemistry (medical), Healthcare, Type 2 Diabetes Mellitus, medicine.disease, biology.organism_classification, Dietary supplements, Obesity, 3. Good health, 030220 oncology & carcinogenesis, Lean body mass, New guidelines, business |
| الوصف: | Due to the important physiologic function of trivalent chromium in glucose/insulin homeostasis, some commercial organisations promote Cr3+ supplements in maintaining proper carbohydrate and lipid metabolism; regulation of reducing carbohydrate carvings and appetite; prevention of insulin resistance and glucose intolerance; regulation of body composition, including reducing fat mass and increasing lean body mass; optimal body building for athletes; losing weight; treatment of atypical depression as an antidepressant; and prevention of obesity and type 2 diabetes mellitus. On one hand, case reports are commented as ‘nonevidence-based anecdotes’. On the other hand, a number of independent studies warn against adverse health outcomes assigned to chromium picolinate (CrPic) dietary application. This review analyses opinion controversies, demonstrates highly individual reactions towards CrPic dietary supplements and highlights risks when the dietary supplements are used freely as therapeutic agents, without application of advanced diagnostic tools to predict individual outcomes. |
| اللغة: | English |
| تدمد: | 1878-5085 1878-5077 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9bf2122b30c165506f56aa78e4fbac http://europepmc.org/articles/PMC3515400 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1b9bf2122b30c165506f56aa78e4fbac |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 18785085 18785077 |
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