Serum carcinoembryonic antigen elevation in benign lung diseases
| العنوان: | Serum carcinoembryonic antigen elevation in benign lung diseases |
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| المؤلفون: | Xiaolin Jiang, Mingfang Xu, Huan Huang, Yi Yang, Xunjie Kuang, Xueqin Yang, Yun Liu, Kan Gong |
| المصدر: | Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021) Scientific Reports |
| بيانات النشر: | Nature Portfolio, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Lung Diseases, Male, medicine.medical_specialty, Adolescent, Science, Comorbidity, Endocrine System Diseases, Gastroenterology, Article, Diagnosis, Differential, Young Adult, Carcinoembryonic antigen, Medical research, Internal medicine, medicine, Diabetes Mellitus, Humans, Lung cancer, Child, Pneumonitis, Cancer, Aged, Retrospective Studies, Aged, 80 and over, COPD, Multidisciplinary, Lung, biology, business.industry, Interstitial lung disease, Age Factors, Middle Aged, medicine.disease, Carcinoembryonic Antigen, medicine.anatomical_structure, Oncology, Cardiovascular Diseases, biology.protein, Medicine, Female, business, Pulmonary alveolar proteinosis, Biomarkers |
| الوصف: | Carcinoembryonic antigen (CEA) is not only used to aid the diagnosis of lung cancer, but also help monitor recurrence and determine the prognosis of lung cancer as well as evaluate the therapeutic efficacy for lung cancer. However, studies have also shown that CEA is present at low levels in the serum of patients with benign lung diseases (BLD), which will interfere with the accurate judgment of the disease. Due to difference in sample size, detection methods, cutoff values and sources of BLD, the positive rate of CEA in BLD is different with different literature. Therefore, it is necessary to define CEA levels in patients of different BLD in a large sample study. 4796 patients with BLD were included in this study. The results showed that the CEA levels of 3.1% (149/4796) patients with BLD were elevated, with three cases exceeds 20 ng/mL (0.06%, 3/4796). The results from the literature showed that BLD had a mean positive rate of 5.99% (53/885) and only two cases had CEA above 20 ng/mL. The CEA elevations mainly distributed in chronic obstructive pulmonary disease (COPD), pneumonitis and interstitial lung disease and significantly correlated with age of patients (OR 2.69, 95% CI 1.94–3.73, p |
| اللغة: | English |
| تدمد: | 2045-2322 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29db2c6b833ad91b31bbe89ba62a07d6 https://doaj.org/article/924e05edb5b444b78cebd69ab1fc4b93 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....29db2c6b833ad91b31bbe89ba62a07d6 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 20452322 |
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