Diversity of porcine reproductive and respiratory syndrome virus in Shandong, China

التفاصيل البيبلوغرافية
العنوان: Diversity of porcine reproductive and respiratory syndrome virus in Shandong, China
المؤلفون: Jing-Jiao Ma, Yujie Li, Zouran Lan, Sun Shengfu, Ruixue Xue, Feng Chen, Guisheng Wang, Zhang Yue, Yungang Li, Wei Xuehua, Miaoli Wang
المصدر: Acta virologica. 65(3)
سنة النشر: 2021
مصطلحات موضوعية: China, Genotype, Sequence analysis, Swine, animal diseases, viruses, Porcine Reproductive and Respiratory Syndrome, Biology, Genetic analysis, Phylogenetics, Virology, Genetic variation, Animals, Porcine respiratory and reproductive syndrome virus, Gene, Phylogeny, Phylogenetic tree, virus diseases, Genetic Variation, General Medicine, respiratory system, Porcine reproductive and respiratory syndrome virus, biology.organism_classification, Infectious Diseases
الوصف: Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically significant pathogens in swine industry of China. To study infection and genetic variation of PRRSV, 637 tissue samples were collected from diseased pigs in Shandong, and then subjected to detection of PRRSV. The nsp2 and ORF5 genes were sequenced for investigation of variations and phylogenetic analysis. The results showed that positive rate of PRRSV was 9.58% in the collected samples. Phylogenetic analysis of GP5 showed that these strains were clustered into two lineages (1 and 8) indicating different genotypes of PRRSV were circulating in Shandong province. Meanwhile, sequence analysis Of nsp2 showed that the PRRSV strains with 30 amino acids deletions were dominant. Moreover, novel pattern of recombination/deletion and insertion in nsp2 was observed in these strains, indicating that novel PRRSV strains with different patterns of deletions or insertions in nsp2 are emerging in China. All the results suggested that continuous surveillance of PRRSV in China is warranted. Keywords: PRRSV; GP5; nsp2; genetic analysis; Shandong.
تدمد: 0001-723X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bea321a1c2648322d9893ab0d4b8a7f
https://pubmed.ncbi.nlm.nih.gov/34565158
رقم الأكسشن: edsair.doi.dedup.....2bea321a1c2648322d9893ab0d4b8a7f
قاعدة البيانات: OpenAIRE