Sarcopenia Is Not a Prognostic Factor of Outcome in Patients With Cervical Cancer Undergoing Concurrent Chemoradiotherapy or Radiotherapy

التفاصيل البيبلوغرافية
العنوان: Sarcopenia Is Not a Prognostic Factor of Outcome in Patients With Cervical Cancer Undergoing Concurrent Chemoradiotherapy or Radiotherapy
المؤلفون: Susumu Kanazawa, Keiichiro Nakamura, Yuko Matsubara, Naoyuki Ida, Chikako Ogawa, Hisashi Masuyama, Kuniaki Katsi, Hirofumi Matsuoka, Takeshi Nishida
المصدر: Anticancer research. 39(2)
سنة النشر: 2018
مصطلحات موضوعية: Oncology, Adult, Cancer Research, Poor prognosis, medicine.medical_specialty, Prognostic factor, Sarcopenia, medicine.medical_treatment, Brachytherapy, Uterine Cervical Neoplasms, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Medicine, Humans, In patient, Muscle, Skeletal, Aged, Psoas Muscles, Retrospective Studies, Cervical cancer, Aged, 80 and over, business.industry, General Medicine, Chemoradiotherapy, Middle Aged, medicine.disease, Prognosis, Concurrent chemoradiotherapy, Predictive factor, Radiation therapy, Treatment Outcome, ROC Curve, 030220 oncology & carcinogenesis, Lymphatic Metastasis, Female, business, Tomography, X-Ray Computed
الوصف: Background/aim The objective of this study was to determine if sarcopenia was a predictor of poor prognosis in patients with cervical cancer (CC) undergoing concurrent chemoradiation therapy (CCRT) or radiation therapy (RT). Materials and methods A total of 236 patients with CC undergoing CCRT or RT were retrospectively examined. We determined if clinical characteristics and survival were correlated with pretreatment sarcopenia, measured as psoas muscle index (PI) or skeletal muscle index (SMI). Results Pretreatment PI and SMI were related to parametrial involvement with CC undergoing CCRT or RT (p=0.002, and, p=0.034, respectively). The median progression-free survival (PFS) and overall survival (OS) times in patients undergoing CCRT or RT were 29.0 and 34.5 months, respectively. Neither PI nor SMI were prognostic predictors in patients with CC undergoing CCRT or RT. Conclusion Sarcopenia is not a predictive factor of outcome in patients with CC undergoing CCRT or RT.
تدمد: 1791-7530
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9e409869759990c859e7b4a8c5200d
https://pubmed.ncbi.nlm.nih.gov/30711978
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....2d9e409869759990c859e7b4a8c5200d
قاعدة البيانات: OpenAIRE