Prognostic nutritional index as a predictor of survival in patients with recurrent cervical cancer
العنوان: | Prognostic nutritional index as a predictor of survival in patients with recurrent cervical cancer |
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المؤلفون: | Keiichiro Nakamura, Hisashi Masuyama, Masayuki Saijo, Tomoyuki Kusumoto, Naoyuki Ida |
المصدر: | Molecular and Clinical Oncology |
بيانات النشر: | Spandidos Publications, 2017. |
سنة النشر: | 2017 |
مصطلحات موضوعية: | 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Multivariate analysis, recurrent cervical cancer, Recurrent cervical cancer, Disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Neutrophil to lymphocyte ratio, Univariate analysis, business.industry, Univariate, Cancer, Articles, prognostic nutritional index, poor prognosis, medicine.disease, Molecular medicine, 030104 developmental biology, 030220 oncology & carcinogenesis, business |
الوصف: | Systemic inflammatory responses (SIRs) can help predict survival in various cancers. The present study investigated the accuracy of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and prognostic nutritional index (PNI) in predicting survival for patients with recurrent cervical cancer. A retrospective review of prognoses examined the associations among NLR, PLR, and PNI, and clinical characteristics and survival in 79 patients with recurrent cervical cancer after undergoing concurrent chemoradiation therapy (CCRT) or radical hysterectomies with or without CCRT. The Mann-Whitney U-test was used for statistical analyses. In addition, 12-month, 24-month and overall survival were analyzed by the Kaplan-Meier method. Cox's proportional hazard regression was used for univariate and multivariate analyses. Median survival was 15.0 months over follow-up periods of 2–93 months. At the last follow-up point, 54 had succumbed to disease and 25 were alive with disease. In univariate analysis, NLR, PLR and PNI were significantly associated with 12-month, 24 month and overall survival (12 months: P=0.021, P=0.001 and P |
تدمد: | 2049-9469 2049-9450 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eaab676296a2d71e5672fea4157bc73 https://doi.org/10.3892/mco.2017.1508 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....2eaab676296a2d71e5672fea4157bc73 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 20499469 20499450 |
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