Interobserver and Intraobserver Variability in pH-Impedance Analysis between 10 Experts and Automated Analysis
| العنوان: | Interobserver and Intraobserver Variability in pH-Impedance Analysis between 10 Experts and Automated Analysis |
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| المؤلفون: | Michiel P. van Wijk, Laura Peeters, Kathleen Blondeau, Rachel Rosen, Taher Omari, Silvia Salvatore, Clara M. Loots, Yvan Vandenplas, Marc A. Benninga, Kasper Dalby, Tobias G. Wenzl |
| المساهمون: | Paediatric Gastroenterology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, General Paediatrics, Pediatric surgery, Pediatrics |
| المصدر: | Loots, C M, van Wijk, M P, Blondeau, K, Dalby, K, Peeters, L, Rosen, R, Salvatore, S, Wenzl, T G, Vandenplas, Y, Benninga, M A & Omari, T I 2011, ' Interobserver and Intraobserver Variability in pH-Impedance Analysis between 10 Experts and Automated Analysis ', Journal of Pediatrics, vol. 16, no. 3, pp. 441-446 . https://doi.org/10.1016/j.jpeds.2011.08.017 Loots, C M, van Wijk, M P, Blondeau, K, Dalby, K, Peeters, L, Rosen, R, Salvatore, S, Wenzl, T G, Vandenplas, Y, Benninga, M A & Omari, T I 2012, ' Interobserver and intraobserver variability in pH-impedance analysis between 10 experts and automated analysis ', Journal of Pediatrics, vol. 160, no. 3, pp. 441-446.e1 . https://doi.org/10.1016/j.jpeds.2011.08.017 Journal of pediatrics, 160(3), 441-U131. Mosby Inc. Journal of Pediatrics, 160(3), 441-446.e1. Mosby Inc. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Observer Variation, Reproducibility, Pathology, medicine.medical_specialty, Esophageal pH Monitoring, medicine.diagnostic_test, Adolescent, business.industry, fungi, Infant, Sensitivity and Specificity, Cohen's kappa, Child, Preschool, Pediatrics, Perinatology and Child Health, pH-impedance, medicine, Gastroesophageal Reflux, Humans, Esophageal pH monitoring, Nuclear medicine, business, Observer variation, Child, Kappa |
| الوصف: | Objective To determine interobserver and intraobserver variability in pH-impedance interpretation between experts and accuracy of automated analysis (AA). Study design Ten pediatric 24-hour pH-impedance tracings were analyzed by 10 observers from 7 world groups and with AA. Detection of gastroesophageal reflux (GER) episodes was compared between observers and AA. Intraobserver agreement was assessed in 3 observers after 3 to 5 months. Results Overall, 1242 liquid and mixed GER events were detected, 490 (42%) were scored by the majority of observers, yielding moderate agreement (Cohen's kappa [kappa] = 0.46). Intraclass co-efficient for numbers of GER per study was 0.84 (P = 6 observers). Agreement for gas GER was poor (kappa = 0.11). Intraobserver agreement was kappa = 0.49, kappa = 0.71, and kappa = 0.85 in 3 observers. Conclusion Interobserver agreement in combined pH-multichannel intraluminal impedance analysis in experts is moderate; only 42% of GER episodes were detected by the majority of observers. Detection of total GER numbers is more consistent. Considering these poor outcomes, AA seems favorable compared with manual analysis because of its reproducibility. However, the lower specificity rate suggests the need for refinement of AA before widespread use can be advocated. (J Pediatr 2012; 160:441-6) |
| اللغة: | English |
| تدمد: | 0022-3476 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35095dee8ece7113ebfe41b1ff1612bf https://doi.org/10.1016/j.jpeds.2011.08.017 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....35095dee8ece7113ebfe41b1ff1612bf |
| قاعدة البيانات: | OpenAIRE |
Full Text via ClinicalKey | تدمد: | 00223476 |
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