The Nuclear Receptor Nor-1 Is a Pleiotropic Regulator of Exercise-Induced Adaptations
| العنوان: | The Nuclear Receptor Nor-1 Is a Pleiotropic Regulator of Exercise-Induced Adaptations |
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| المؤلفون: | George E.O. Muscat, Michael A. Pearen |
| المصدر: | Exercise and Sport Sciences Reviews. 46:97-104 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Sarcomeres, 0301 basic medicine, Muscle Fibers, Skeletal, Regulator, Gene Expression, Physical Therapy, Sports Therapy and Rehabilitation, Biology, 03 medical and health sciences, 0302 clinical medicine, Nuclear Receptor Subfamily 4, Group A, Member 3, Gene expression, Autophagy, medicine, Animals, Humans, Orthopedics and Sports Medicine, Calcium Signaling, Exercise physiology, Muscle, Skeletal, Exercise, Transcription factor, Calcium signaling, Skeletal muscle, Adaptation, Physiological, Mitochondria, Muscle, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Nuclear receptor, sense organs, 030217 neurology & neurosurgery |
| الوصف: | Exercise induces various physical and metabolic changes in skeletal muscle that adaptively reprograms this tissue to current physiological and environmental demands. Underlying these changes are broad modifications to gene expression. We postulate that the nuclear hormone receptor, Nor-1, is activated after exercise, and this transcription factor modifies gene expression to drive the molecular and cellular adaptations associated with contractile reorganization. |
| تدمد: | 1538-3008 0091-6331 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37dc3b9371dfa25306432132b4555448 https://doi.org/10.1249/jes.0000000000000143 |
| رقم الأكسشن: | edsair.doi.dedup.....37dc3b9371dfa25306432132b4555448 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15383008 00916331 |
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